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Apta-Index™: Xanthine (XAB) (ID# 103)

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Xanthine (XAB) (ID# 103)

Xanthine (XAB)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Xanthine Small Organic 3.3 nM (reported value) Binding Buffer (20 mM Tris–HCl (pH 7.5), 0.3 M NaCl and 5 mM MgCl2) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprGprCprAprCprGprUprGprUprAprUprUprAprCprCprCprUprAprGprUprGprGprUprCprGprAprCprGprUprGprCprCp-3'
32 10232.17 g/mole 307700.00 L/(mole·cm) 59.38% 3.25 33.25

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Kiga, D., et al. "An RNA aptamer to the xanthine/guanine base with a distinctive mode of purine recognition." Nucleic Acids Research, 26 (1998): 1755-1760.

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