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Aptamer Details

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Small-Cell Lung Cancer (HCH07) (ID# 69)

Small-Cell Lung Cancer (HCH07)
DNA Small-cell lung cancer (SCLC) cell-surface molecular markers Cells 38 nM (reported value) Washing Buffer (4.5 g/L Glucose, 5mM MgCl2, and 1 mg/mL BSA in Dulbecco's PBS (pH 7.3)) Binding Buffer (wash buffer and 0.1 mg/mL yeast tRNA) 4°C NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'dTpdApdCpdCpdApdGpdTpdGpdCpdGpdApdTpdGpdCpdTpdCpdApdGpdGpdCpdCpdGpdApdTpdGpdTpdCpdApdApdCpdTpdTpdTpdTpdTpdCpdTpdApdApdCpdTpdCpdApdCpdTpdGpdGpdTpdTpdTpdTpdGpdCpdCpdTpdGpdApdCpdGpdCpdApdTpdTpdCpdGpdGpdTpdTpdGpdApdCp3' 71 21768.15 g/mole 650200 L/(mole·cm) 49.30% 1.54 33.48

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Chen, Hui, et al. "Molecular Recognition of Small-Cell Lung Cancer Cells Using Aptamers." CHEMMEDCHEM, 3 (2008): 991-1001.

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